Perineurial Glia
نویسندگان
چکیده
منابع مشابه
Perineurial glia.
Although the ultrastructure of peripheral nerves has been known for nearly 200 years, the developmental origins and functional roles of all five main components of these specialized nervous system conduits are still poorly understood. One of these understudied nerve elements, the perineurium, is a component of the blood-nerve barrier and is essential for protecting axons and their associated Sc...
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Ethanol is the most common drug of abuse. It exerts its behavioral effects by acting on widespread neural circuits; however, its impact on glial cells is less understood. We show that Drosophila perineurial glia are critical for ethanol tolerance, a simple form of behavioral plasticity. The perineurial glia form the continuous outer cellular layer of the blood-brain barrier and are the interfac...
متن کاملPerineurial glia require Notch signaling during motor nerve development but not regeneration.
Motor nerves play the critical role of shunting information out of the CNS to targets in the periphery. Their formation requires the coordinated development of distinct cellular components, including motor axons and the Schwann cells and perineurial glia that ensheath them. During nervous system assembly, these glial cells must migrate long distances and terminally differentiate, ensuring the e...
متن کاملSpinal perineurial and meningeal cysts.
Perineurial cysts may be responsible for clinical symptoms and a cure effected by their removal. They do not fill on initial myelography but may fill with Pantopaque some time, days or weeks, after Pantopaque has been instilled into the subarachnoid space. Perineurial cysts arise at the site of the posterior root ganglion. The cyst wall is composed of neural tissue. When initial myelography fai...
متن کاملSymptomatic sacral perineurial (Tarlov) cysts.
Sacral perineurial (Tarlov) cysts are rare lesions. Over a seven year period 4000 patients underwent surgery for lumbar disk herniation. In three patients neurological symptoms were caused by large sacral perineurial cysts. Methods of choice for diagnosis of Tarlov cysts are lumbosacral magnetic resonance imaging and computerized tomography myelography. The majority of Tarlov cysts are asymptom...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2015
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a020511